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Effect of sequence homology on PDB-based PREDITOR predictions of χ-1 angles.

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Figure above illustrates dependence of accuracy of PDB-based PREDITOR predictions of χ-1 angles on sequence identity.  A total of 31 different query proteins were used, each with an average of 5.5 homologues in the PDB, yielding a plot with nearly 170 data points.  The best-fit linear curve (y=A + B*x, where A = 46.3 ; B = 0.4, correlation coeff. = 0.77) was used to derive the following confidence levels: 

% Sequence Identity

Confidence levels

0-25

0.66

25-50

0.67

50-75

0.75

75-100

0.85


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