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Proteus Structure Prediction Server
Comprehensive Secondary Structure Predictions
 
 
 
Proteus prediction (ID=9766241) complete
Summary:
 
  • Time of Submission: 20:54:57 Apr 01, 2006
  • Sequence Name: 1as4B
  • Number of residues read in: 33
  • No homolog was found
  • Number of sequence alignments used for ab-initio predictions: 30
  • Overall confidence value: 88.2%
  • Predicted % Helix content: 0 % (0 residues)
  • Predicted % Beta sheet content: 61 % (20 residues)
  • Predicted % Coil content: 39 % (13 residues)

Legend:
  H = Helix
E = Beta Strand
C = Coil
Line 1 = sequence (single letter IUPAC code, 60 characters per line)
Line 2 = secondary structure (H, E or C)
Line 3 = confidence score (0-9, 0 = low, 9 = high)

A '*' character above the overall prediction indicates the homolog's structure was used at this residue.

Predicted Secondary Structure:
 
   1  GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ 33
     
CEEEEECCCEEEEEECCCCCEEEEEEEEECCCC
      789996897899998599977999999987898



    Proteus uses a "Jury of Experts" approach involving predictions from PSIPRED ( Jones, 1999 ), JNET ( Barton et al., 1999 ), TRANSSEC (a locally developed tool), and structural alignment ( XALIGN ). Following is the predicted secondary structure from each component.
Detailed Prediction Information:
 

PSIPRED
   1  GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ 33
     
CEEEEECCCEEEEEECCCCCEEEEEEEEECCCC
      958875799899999699984999988768999



JNET
   1  GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ 33
     
CCEEEECCCEEEEEEECCCCEEEEEEEECCCCC
      304661997577888179830678777379987



TRANSSEC
   1  GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ 33
     
CCCCCCCCCEEEEEECCCCCCEEEEEEEECCCC
      977788885799886689985788777767899



JURY-OF-EXPERTS PREDICTION
   1  GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ 33
     
CEEEEECCCEEEEEECCCCCEEEEEEEEECCCC
      789996897899998599977999999987898



PSI-BLAST ALIGNMENTS - 30 SEQUENCES USED BY JNET, TRANSSEC, and PSIPRED
Blast e-value: 1.19195E-9
1   >gi|112874|sp|P01011|AACT_HUMAN Alpha-1-antichymotrypsin precursor (ACT) >gnl|BL_ORD_ID|372268 SERPINA3 protein [Homo sapiens] >gnl|BL_ORD_ID|372268 SERPINA3 protein [Homo sapiens]
match: -TIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 5.62838E-8
2   >gi|2136705|pir||S66289 alpha 1 antichymotrypsin - bovine (fragment) >gnl|BL_ORD_ID|224998 alpha 1-antichymotrypsin; ACT [Bos taurus]
match: --IVRVNRPFLIAIVLKDTQSIIFLGKVTNPSE------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 1.5447E-7
3   >gi|1708609|sp|P29622|KAIN_HUMAN Kallistatin precursor (Kallikrein inhibitor) (Protease inhibitor 4) >gnl|BL_ORD_ID|436695 kallistatin precursor - human >gnl|BL_ORD_ID|436695 kallistatin >gnl|BL_ORD_ID|436695 kallistatin
match: --ILRFNRPFLVVIFSTSTQSVLFLGKVVDPTK------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 1.7361E-7
4   >gi|15079234|gb|AAH11217.1| Serine (or cysteine) proteinase inhibitor, clade A, member 3K [Mus musculus]
match: ---VHFNRPFLFVIYHTSAQSILFMAKVNNPK-------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 1.81006E-7
5   >gi|535509|gb|AAA50448.1| alpha1-antichymotrypsin isoform pHHK12
match: ---VSFNRPFLLSIFCKETQSIIFVGKVTNPKE------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 2.46472E-7
6   >gi|416561|sp|P32759|A1AT_CYPCA Alpha-1-antitrypsin homolog precursor >gnl|BL_ORD_ID|143552 alpha-1-antitrypsin precursor - common carp >gnl|BL_ORD_ID|143552 alpha-1 antitrypsin
match: ---VILNRPFLVLIVEDTTKSILFMGKITNPTE------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 2.65694E-7
7   >gi|21309939|gb|AAM46107.1| alpha-1-antitrypsin [Sphenodon punctatus]
match: --VVKLNRPFLFSIVDKTAHSVLFMGKVVNPKE------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 2.77012E-7
8   >gi|220698|dbj|BAA00648.1| contrapsin-like protease inhibitor (CPi-21) [Rattus norvegicus]
match: --LLNFNRPFMLVITDNNGQSVFFMGKVTNP--------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 3.86763E-7
9   >gi|2507387|sp|P05544|CPI3_RAT CONTRAPSIN-LIKE PROTEASE INHIBITOR 3 PRECURSOR (CPI-23) (SERINE PROTEASE INHIBITOR 1) (SPI-1) >gnl|BL_ORD_ID|372885 contrapsin-like protease inhibitor related protein (CPi-23) [Rattus norvegicus]
match: ---LNFNRPFMVVITDMDSQSILFVAKITNPK-------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 2.01803E-6
10  >gi|9955853|emb|CAC05490.1| alpha-1-antichymotrypsin 2 [Sus scrofa]
match: ---LHFNRPFLFVIISKDIQSIIFLGKVTKP--------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 5.63164E-6
11  >gi|1703026|sp|P50447|A1AT_PIG ALPHA-1-ANTITRYPSIN PRECURSOR (ALPHA-1 PROTEASE INHIBITOR) (ALPHA-1-ANTIPROTEINASE) >gnl|BL_ORD_ID|324307 alpha-1-antitrypsin [Sus scrofa]
match: ---VKFNKPFLFLIYDTKTKAVLFMGKVMNPTQ------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 3.08929E-5
12  >gi|21490001|ref|NP_659565.1| kallistatin [Rattus norvegicus] >gnl|BL_ORD_ID|280008 kallistatin
match: ---LIFNRPFLVILYSTSSQDILFMGKVVNPT-------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 6.12347E-5
13  >gi|37545994|ref|XP_170754.3| similar to serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4; protease inhibitor 4 (kallistatin) [Homo sapiens]
match: ----HFNRPFLLLLWEVTTQSLLFLGKVVNP--------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 6.99803E-5
14  >gi|477547|pir||A49190 corticosteroid-binding globulin - sheep
match: ---LRFNRPFIIMIFDDFTWSSLFLGKVVNPTE------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 7.11579E-5
15  >gi|54175|emb|CAA49486.1| serine proteinase inhibitor 2.4 [Mus musculus]
match: ---VQFNRPFLMVISHTGVQTTLFMAKVTNPK-------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 7.54377E-5
16  >gi|112887|sp|P26595|A1AT_MUSCR Alpha-1-antiproteinase precursor (Alpha-1-antitrypsin) (Alpha-1-proteinase inhibitor) (AAT) >gnl|BL_ORD_ID|614002 alpha-1-antitrypsin precursor - ricefield mouse (Mus caroli) >gnl|BL_ORD_ID|614002 alpha-1-antitrypsin (AT)
match: --ILNFNKPFIFIIVEEHTQSPLFVGKVVDPTR------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 1.16417E-4
17  >gi|3982489|gb|AAC83412.1| alpha-1-antitrypsin; serine protease inhibitor [Equus caballus]
match: ---LKFNRPFVLIIYDRNTKSPLFVGKVVDPTQ------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 1.25496E-4
18  >gi|27806941|ref|NP_776307.1| serine (or cysteine) proteinase inhibitor, clade A (alpha-1antiproteinase, antitrypsin), member 1; protease inhibitor 1 (anti-elastase, antitrypsin, alpha-1) [Bos taurus] >gnl|BL_ORD_ID|814022 Alpha-1-antiproteinase precursor (Alpha-1-antitrypsin) (Alpha-1-proteinase inhibitor) >gnl|BL_ORD_ID|814022 alpha-1-antitrypsin precursor - bovine >gnl|BL_ORD_ID|814022 alpha-1-antitrypsin [Bos taurus]
match: ---VEFNRPFLCILYDRNTKSPLFVGKVVNPTQ------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 1.76685E-4
19  >gi|6686383|sp|O54760|ALSI_TAMSI Alpha-1-antitrypsin-like protein CM55-SI precursor >gnl|BL_ORD_ID|1027092 alpha,-antitrypsin-like protein [Tamias sibiricus]
match: ---VIFDRPFLVVIYEHHTKSPLFVGKVVNPTQ------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 2.36607E-4
20  >gi|6685945|sp|Q60396|SI24_APOSY Serine proteinase inhibitor 2.4 precursor >gnl|BL_ORD_ID|1047679 serine proteinase inhibitor 2.4 - European woodmouse >gnl|BL_ORD_ID|1047679 serine proteinase inhibitor 2.4 [Apodemus sylvaticus]
match: ---VRFDRPFLMVVSHTGVESILFLAKVTNP--------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 3.16851E-4
21  >gi|223433|prf||0805684B inhibitor,alpha1 protease
match: ---VKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 3.16851E-4
22  >gi|31745162|ref|NP_853661.1| serine proteinase inhibitor HongrES1 [Rattus norvegicus] >gnl|BL_ORD_ID|362871 serine proteinase inhibitor HongrES1 [Rattus norvegicus]
match: ---LHFNRSFLLLILDETSNSLLFMGKVVNPTR------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 4.17288E-4
23  >gi|10720311|sp|Q9TT35|THBG_PIG Thyroxine-binding globulin precursor (T4-binding globulin) >gnl|BL_ORD_ID|656854 thyroxine-binding globulin [Sus scrofa]
match: --IIQFDRSFLLLILEKSTRSILFLGKVVDPTE------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 4.3871E-4
24  >gi|2118386|pir||I56481 alpha 1-proteinase inhibitor - spiny mouse (Mus saxicola) >gnl|BL_ORD_ID|315553 alpha 1-proteinase inhibitor; alpha 1PI [Mus saxicola]
match: --ILHFNHPFVFTIVETHTQTPLFVGKVVDPTR------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 5.31522E-4
25  >gi|34980957|gb|AAH57144.1| Serpina3g protein [Mus musculus]
match: -----FNRPFLMIISDTKAHIALFMAKVTNPER------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 5.49561E-4
26  >gi|2804193|dbj|BAA24421.1| alpha,-antitrypsin-like protein [Spermophilus tridecemlineatus]
match: ---VKFNRPFLVTLYDRSTKSPLFVGRVVNPT-------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 6.54806E-4
27  >gi|348255|pir||S31505 serine proteinase inhibitor 2.4 - rat (fragment) >gnl|BL_ORD_ID|269497 serine protease inhibitor 2.4 [Rattus norvegicus]
match: --IVWFNRPFLIAVSHTHGQHILFMAKVINP--------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 6.71403E-4
28  >gi|15029662|gb|AAH11040.1| Serine (or cysteine) proteinase inhibitor, clade A, member 1a [Mus musculus] >gnl|BL_ORD_ID|649879 DOM1 [Mus musculus] >gnl|BL_ORD_ID|649879 Serine (or cysteine) proteinase inhibitor, clade A, member 1a [Mus musculus] >gnl|BL_ORD_ID|649879 Serine (or cysteine) proteinase inhibitor, clade A, member 1a [Mus musculus] >gnl|BL_ORD_ID|649879 Serine (or cysteine) proteinase inhibitor, clade A, member 1a [Mus musculus] >gnl|BL_ORD_ID|649879 Serine (or cysteine) proteinase inhibitor, clade A, member 1a [Mus musculus]
match: --ILRFDHPFLFIIFEEHTQSPIFVGKVVDPT-------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 8.84227E-4
29  >gi|3205171|dbj|BAA28760.1| ATS-22 [Oryctolagus cuniculus]
match: ---VTFDRPFLFVIYSHEVKSPLFVGKVVDPTQ------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

Blast e-value: 9.85533E-4
30  >gi|31199799|ref|XP_308847.1| ENSANGP00000021651 [Anopheles gambiae] >gnl|BL_ORD_ID|523282 ENSANGP00000021651 [Anopheles gambiae str. PEST]
match: ------NRPFLFYILDEETNAILFVGKVTDPSR------------------
query: GTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ------------------

                        

3D Structures:
No homolog was found for your sequence.